Pauline Cafferkey (Ebola Patient)
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Ebola virus disease in the United Kingdom and Ireland has occurred rarely in four cases to date, namely three health workers returning from treating victims of the
Ebola virus epidemic in West Africa The 2013–2016 epidemic of Ebola virus disease, centered in West Africa, Western Africa, was the most widespread List of Ebola outbreaks, outbreak of the disease in history. It caused major loss of life and Socioeconomics, socioeconomic disr ...
in 2014 and 2015, and a single case in 1976, when a laboratory technician contracted the disease in a
needlestick injury A needlestick injury is the penetration of the skin by a hypodermic needle or other sharp object that has been in contact with blood, tissue or other body fluids before the exposure. Even though the acute physiological effects of a needlestick i ...
while handling samples from Africa. All cases recovered. As of 2023, no domestic transmission of Ebola has occurred in the United Kingdom or Ireland.


Infected in the UK and Ireland

On 5 November 1976, Geoffrey Platt, a laboratory technician at the former Microbiological Research Establishment in
Porton Down Porton Down is a science park in Wiltshire, England, just northeast of the village of Porton, near Salisbury. It is home to two British government facilities: a site of the Ministry of Defence's Defence Science and Technology Laboratory (Dstl ...
,
Wiltshire Wiltshire (; abbreviated Wilts) is a historic and ceremonial county in South West England with an area of . It is landlocked and borders the counties of Dorset to the southwest, Somerset to the west, Hampshire to the southeast, Gloucestershire ...
, contracted Ebola in an accidental
needlestick injury A needlestick injury is the penetration of the skin by a hypodermic needle or other sharp object that has been in contact with blood, tissue or other body fluids before the exposure. Even though the acute physiological effects of a needlestick i ...
from a contaminated needle while handling samples from Africa. He was treated with human interferon and
convalescent serum Antiserum is a blood serum containing monoclonal or polyclonal antibodies that is used to spread passive immunity to many diseases via blood donation (plasmapheresis). For example, convalescent serum, passive antibody transfusion from a previous ...
. The course of his disease was mild and he fully recovered.


Infected outside UK and Ireland


Nurse, 2014

The
high-level isolation unit In hospitals and other medical facilities, an isolation ward is a separate ward used to isolate patients with infectious diseases. Several wards for individual patients are usually placed together in an isolation unit. Design In an isolation un ...
at the
Royal Free Hospital The Royal Free Hospital (also known simply as the Royal Free) is a major teaching hospital in the Hampstead area of the London Borough of Camden. The hospital is part of the Royal Free London NHS Foundation Trust, which also runs services at Barn ...
, in the
Hampstead Hampstead () is an area in London, which lies northwest of Charing Cross, and extends from Watling Street, the A5 road (Roman Watling Street) to Hampstead Heath, a large, hilly expanse of parkland. The area forms the northwest part of the Lon ...
area of
London London is the capital and largest city of England and the United Kingdom, with a population of just under 9 million. It stands on the River Thames in south-east England at the head of a estuary down to the North Sea, and has been a majo ...
, received its first case on 24 August 2014. William Pooley, a British nurse who contracted the disease while working in
Sierra Leone Sierra Leone,)]. officially the Republic of Sierra Leone, is a country on the southwest coast of West Africa. It is bordered by Liberia to the southeast and Guinea surrounds the northern half of the nation. Covering a total area of , Sierra ...
as part of the relief effort for the
Ebola virus epidemic in West Africa The 2013–2016 epidemic of Ebola virus disease, centered in West Africa, Western Africa, was the most widespread List of Ebola outbreaks, outbreak of the disease in history. It caused major loss of life and Socioeconomics, socioeconomic disr ...
, was medically evacuated by the
Royal Air Force The Royal Air Force (RAF) is the United Kingdom's air and space force. It was formed towards the end of the First World War on 1 April 1918, becoming the first independent air force in the world, by regrouping the Royal Flying Corps (RFC) and ...
on a specially-equipped
C-17 The McDonnell Douglas/Boeing C-17 Globemaster III is a large military transport aircraft that was developed for the United States Air Force (USAF) from the 1980s to the early 1990s by McDonnell Douglas. The C-17 carries forward the name of two ...
aircraft. He was released from hospital on 3 September 2014. Pooley delivered the UK's
Channel 4 Channel 4 is a British free-to-air public broadcast television network operated by the state-owned enterprise, state-owned Channel Four Television Corporation. It began its transmission on 2 November 1982 and was established to provide a four ...
television program ''
Alternative Christmas message The alternative Christmas message is a message broadcast by Channel 4 since 1993, as a sometimes humorous and sometimes serious alternative to the traditional Royal Christmas Message. Background Beginning in 1993, Channel 4 broadcast an "alterna ...
'' in 2014. He was reported to be planning to return to Sierra Leone on 19 October 2014. He also donated blood to support developing a cure for the disease.


Aid worker, 2014

On 29 December 2014,
Pauline Cafferkey Pauline Cafferkey is a Scottish nurse and aid worker who contracted Ebola virus disease in 2014 while working in Sierra Leone as part of the medical aid effort during the West African Ebola virus epidemic. She survived the illness. Initial admis ...
, a Scottish aid worker who had just returned from an Ebola treatment centre in
Kerry Town Kerry Town is a village in the Rural District in the Western Area of Glasgow Glasgow ( ; sco, Glesca or ; gd, Glaschu ) is the most populous city in Scotland and the fourth-most populous city in the United Kingdom, as well as being the 27th largest city by population in Europe. In 2020, it had an estimated popul ...
via
Casablanca Airport Mohammed V International Airport, ; ber, ⴰⵣⴰⴳⵯⵣ ⴰⴳⵔⵖⵍⴰⵏ ⵎⵓⵃⵎⵎⴷ ⵡⵙ5; french: Aéroport International de Mohammed V is an international airport serving Casablanca, Morocco. Located in Nouaceur Province ...
and
London Heathrow Airport Heathrow Airport (), called ''London Airport'' until 1966 and now known as London Heathrow , is a major international airport in London, England. It is the largest of the six international airports in the Airports of London, London airport sys ...
, was diagnosed with Ebola virus disease at Glasgow's
Gartnavel General Hospital Gartnavel General Hospital is a teaching hospital in the West End of Glasgow, Scotland. The hospital is located next to the Great Western Road, between Hyndland, Anniesland and Kelvindale. Hyndland railway station is adjacent to the hospital. T ...
. it was thought she contracted the virus as a result of wearing a visor instead of goggles. Criticism was levelled at screening protocols at UK points of entry, which mainly consisted of taking a person's temperature and asking a series of questions. After initial treatment in Glasgow, she was transferred to the specialist
high-level isolation unit In hospitals and other medical facilities, an isolation ward is a separate ward used to isolate patients with infectious diseases. Several wards for individual patients are usually placed together in an isolation unit. Design In an isolation un ...
at the
Royal Free Hospital The Royal Free Hospital (also known simply as the Royal Free) is a major teaching hospital in the Hampstead area of the London Borough of Camden. The hospital is part of the Royal Free London NHS Foundation Trust, which also runs services at Barn ...
in
London London is the capital and largest city of England and the United Kingdom, with a population of just under 9 million. It stands on the River Thames in south-east England at the head of a estuary down to the North Sea, and has been a majo ...
for longer-term treatment.
Contact tracing In public health, contact tracing is the process of identifying persons who may have been exposed to an infected person ("contacts") and subsequent collection of further data to assess transmission. By tracing the contacts of infected individua ...
was carried out on the other passengers who had traveled on the flight from London to Glasgow with her. In January 2015, she experienced a period of
critical illness Intensive care medicine, also called critical care medicine, is a medical specialty that deals with seriously or critically ill patients who have, are at risk of, or are recovering from conditions that may be life-threatening. It includes pro ...
, and underwent intensive medical treatment. In January 2015 she was declared to be free of infection, and released from hospital. In October 2015, Cafferkey was diagnosed with late complications caused by the Ebola virus hitherto considered unusual, and readmitted to the
Royal Free Hospital The Royal Free Hospital (also known simply as the Royal Free) is a major teaching hospital in the Hampstead area of the London Borough of Camden. The hospital is part of the Royal Free London NHS Foundation Trust, which also runs services at Barn ...
. The virus had remained in her
cerebrospinal fluid Cerebrospinal fluid (CSF) is a clear, colorless body fluid found within the tissue that surrounds the brain and spinal cord of all vertebrates. CSF is produced by specialised ependymal cells in the choroid plexus of the ventricles of the bra ...
and was feared to be in her central nervous system. Her doctors stated that she had been
critically ill Intensive care medicine, also called critical care medicine, is a medical specialty that deals with seriously or critically ill patients who have, are at risk of, or are recovering from conditions that may be life-threatening. It includes pro ...
due to neurological complications from meningitis, and that she had been treated using a highly experimental
anti-viral Antiviral drugs are a class of medication used for treating viral infections. Most antivirals target specific viruses, while a broad-spectrum antiviral is effective against a wide range of viruses. Unlike most antibiotics, antiviral drugs do no ...
agent. On 12 November the Royal Free Hospital said that Cafferkey had made a full recovery and was no longer infectious. In February 2016, Cafferkey was readmitted to the Royal Free Hospital due to complications from her infection, but later that month declared not to be infectious and discharged. In October 2016, she was again admitted to hospital, monitored by the infectious diseases unit at Glasgow's
Queen Elizabeth University Hospital The Queen Elizabeth University Hospital (QEUH) is a 1,677-bed acute hospital located in Govan, in the south-west of Glasgow, Scotland. The hospital is built on the site of the former Southern General Hospital and opened at the end of April 2015. ...
, but tests for the Ebola virus were negative. In 2016, proceedings were initiated against Cafferkey by the
Nursing and Midwifery Council The Nursing and Midwifery Council (NMC) is the regulator for nursing and midwifery professions in the UK. The NMC maintains a register of all nurses, midwives and specialist community public health nurses and nursing associates eligible to prac ...
alleging that she had allowed an incorrect temperature to be recorded during the screening process upon returning to the UK from Sierra Leone in 2014. Following a hearing in September 2016, the charges against her were dismissed after the disciplinary panel was told that she had been impaired by illness at the time.


Military health worker, 2015

On 11 March 2015, a UK military health worker contracted the disease in Sierra Leone while volunteering as a nurse. After testing positive for Ebola she was flown home for treatment at Royal Free Hospital in London. On 27 March 2015 Corporal Anna Cross, the UK military worker who tested positive for Ebola, was the first person in the world to be treated with the experimental Ebola drug MIL 77 and was released from hospital after making a full recovery. The doctors treating her at London's Royal Free Hospital confirmed it is too soon to speculate if the drug helped in her recovery.


Suspected, but not confirmed incidents

Healthcare workers who in January 2015 had sustained
needlestick injuries A needlestick injury is the penetration of the skin by a hypodermic needle or other sharp object that has been in contact with blood, tissue or other body fluids before the exposure. Even though the acute physiological effects of a needlestick i ...
while caring for Ebola patients abroad were put under medical observation, but not found to have contracted the Ebola virus. On 16 March 2015, another UK worker had been sent back to the United Kingdom from Sierra Leone due to fear of having contracted the virus. but did not test positive. On 17 November
Colchester Hospital Colchester Hospital is a district general hospital located in Colchester, Essex. It is managed by East Suffolk and North Essex NHS Foundation Trust. History The hospital, then named Colchester District General Hospital, was opened by Queen Eliza ...
deep cleaned after a suspected case of the
2022 Uganda Ebola outbreak The 2022 Uganda Ebola outbreak was an outbreak of the Sudan ebolavirus, which causes Ebola, from 20 September 2022 until 10 January 2023 in the Western and Central Regions of Uganda. Over 160 people were infected, including 77 people who died. ...
, which as of December was not confirmed as an Ebola case.


Public health measures

In November 2014,
Public Health England Public Health England (PHE) was an executive agency of the Department of Health and Social Care in England which began operating on 1 April 2013 to protect and improve health and wellbeing and reduce health inequalities. Its formation came as a ...
established the returning workers scheme, mandating organisations and businesses to register and provide travel details of all staff returning from Ebola affected areas before they travel back to the UK. In October 2022, the UK Health Security Agency issued a health alert asking providers to considering Ebola in the
differential diagnosis In healthcare, a differential diagnosis (abbreviated DDx) is a method of analysis of a patient's history and physical examination to arrive at the correct diagnosis. It involves distinguishing a particular disease or condition from others that p ...
of any patient with relevant symptoms returning from areas affected by the outbreak of Sudan ebolavirus in Uganda.


See also

*
United Kingdom aid efforts for the 2014 Ebola epidemic in West Africa In late October 2014, the United Kingdom sent a hospital ship, the Royal Fleet Auxiliary's ''Argus'', to help the aid effort against the Ebola virus disease epidemic in Sierra Leone. By late October Sierra Leone was experiencing more than twenty ...
*
List of Ebola outbreaks This list of Ebola outbreaks records the known occurrences of Ebola virus disease, a highly infectious and acutely lethal viral disease that has afflicted humans and animals primarily in equatorial Africa. The pathogens responsible for the di ...
*
National Health Service The National Health Service (NHS) is the umbrella term for the publicly funded healthcare systems of the United Kingdom (UK). Since 1948, they have been funded out of general taxation. There are three systems which are referred to using the " ...
(U.K.)


References


Further reading

* {{Use dmy dates, date=March 2020
United Kingdom The United Kingdom of Great Britain and Northern Ireland, commonly known as the United Kingdom (UK) or Britain, is a country in Europe, off the north-western coast of the continental mainland. It comprises England, Scotland, Wales and North ...
Disease outbreaks in the United Kingdom 2014 in the United Kingdom Ebola